Does anyone know an easy way to get a bed/gff or any text file with annotation information for a transcriptome? The exact issue is the following: Have aligned mRNAseq data to ensembl cDNA v56 fasta file. Created a custom genome in IGV so I can look at the alterations in my pileup file. What would help is to be able to load a bed/gff file that identifies at least the CDS space of each transcript and better yet the exons and amino acids if I can have my cake and eat it too. I've found lots of downloads that annotate the transcriptome to genome but not the entire transcriptome to the transcriptome.

Clairification: I have data that maps the transcript segments to the various genome versions. What I'm hoping to find is annotations akin to a Genebank file for a specific transcript (ie. 1-2300=Gene, 46-2134=CDS, 1-500=Exon1, 501-1300=Exon2, 1301-2300=Exon3, etc...) but instead of each transcript I want it in a table format for the entire transcriptome. This does not seem possible on UCSC for instance as all tracks are mapped to the genome.

asked 17 May '10, 02:00

jon_keats's gravatar image

jon_keats
1614
accept rate: 0%

edited 26 May '10, 13:07

Hi Jon, nice to see you over here! :)

(17 May '10, 02:16) ECO ♦♦

The UCSC table browser is one place to obtain gene and mRNA tracks in .bed format

http://genome.ucsc.edu/cgi-bin/hgTables?org=Human&db=hg19&hgsid=155229247&hgta_doMainPage=1

You might need to parse the files appropriately, but it seems they have the information you are looking for.

link

answered 21 May '10, 11:54

bioinfosm's gravatar image

bioinfosm
1067
accept rate: 0%

Your answer
toggle preview

Follow this question

By Email:

Once you sign in you will be able to subscribe for any updates here

By RSS:

Answers

Answers and Comments

Markdown Basics

  • *italic* or _italic_
  • **bold** or __bold__
  • link:[text](http://url.com/ "title")
  • image?![alt text](/path/img.jpg "title")
  • numbered list: 1. Foo 2. Bar
  • to add a line break simply add two spaces to where you would like the new line to be.
  • basic HTML tags are also supported

Tags:

×6
×5
×1

Asked: 17 May '10, 02:00

Seen: 1,147 times

Last updated: 26 May '10, 13:07

powered by OSQA